2. DNA-Intercalating Supramolecular Hydrogels for Tunable Thermal and Viscoelastic Properties

Shaina M. Hughes,* Aylin Aykanat,* Nicholas G. Pierini, Wynter A. Paiva, April A. Weeks, Austin S. Edwards, Owen C. Durant, Nathan John Oldenhuis

*Denotes Equal Contribution

Angewandte Chemie International Edition 2024 Accepted Article

1. From Bioreactor to Bulk Rheology: Achieving Scalable Production of Highly Concentrated Circular DNA

Wynter A Paiva, Somkene D Alakwe, Juexin Marfai, Madigan Jennison‐Henderson, Rachel A Achong, Tinotenda Duche, April Weeks, Rae M Robertson‐Anderson, Nathan J Oldenhuis

Advanced Materials, 2024 2405490

Previous Publications

From undergraduate, graduate, and postdoctoral studies

18. Nested non-covalent interactions expand the functions of supramolecular polymer networks

David J Lundberg, Christopher M Brown, Eduard O Bobylev, Nathan J Oldenhuis, Yasmeen S Alfaraj, Julia Zhao, Ilia Kevlishvili, Heather J Kulik, Jeremiah A Johnson

Nature Communications 2024 15 (1), 3951    

17. Photoswitchable Sol–Gel Transitions and Catalysis Mediated by Polymer Networks with Coumarin‐Decorated Cu24L24 Metal–Organic Cages as Junctions

Nathan J Oldenhuis, K Peter Qin, Shu Wang, Hong‐Zhou Ye, Eric A Alt, Adam P Willard, Troy Van Voorhis, Stephen L Craig, Jeremiah A Johnson

Angewandte Chemie International Edition 2022 59 (7), 2784-2792

16. Polymer Networks with Cubic, Mixed Pd(II) and Pt(II) M6L12 Metal–Organic Cage Junctions: Synthesis and Stress Relaxation Behavior

Julia Zhao, Eduard O Bobylev, David J Lundberg, Nathan J Oldenhuis, Heng Wang, Ilia Kevlishvili, Stephen L Craig, Heather J Kulik, Xiaopeng Li, Jeremiah A Johnson

Journal of the American Chemical Society 2023 145 (40), 21879-21885

15. Endohedrally functionalized metal–organic cage-cross-linked polymer gels as modular heterogeneous catalysts

Christopher M Brown, David J Lundberg, Jessica R Lamb, Ilia Kevlishvili, Denise Kleinschmidt, Yasmeen S Alfaraj, Heather J Kulik, Maria Francesca Ottaviani, Nathan J Oldenhuis, Jeremiah A Johnson

Journal of the American Chemical Society 2022 144 (29), 13276-13284

14. Greener methods for amide bond synthesis

Nathan J Oldenhuis, Aaron M Whittaker, Vy M Dong

Green Chemistry in Drug Discovery: From Academia to Industry, 2022 35-96

13. Photoswitchable Sol–Gel Transitions and Catalysis Mediated by Polymer Networks with Coumarin‐Decorated Cu24L24 Metal–Organic Cages as Junctions

Nathan J Oldenhuis, K Peter Qin, Shu Wang, Hong‐Zhou Ye, Eric A Alt, Adam P Willard, Troy Van Voorhis, Stephen L Craig, Jeremiah A Johnson

Angewandte Chemie International Edition 2020 59 (7), 2784-2792

12. Brush-first and ROMP-out with functional (macro) monomers: method development, structural investigations, and applications of an expanded brush-arm star polymer platform

Matthew R Golder, Hung V-T Nguyen, Nathan J Oldenhuis, Julian Grundler, Ellane J Park, Jeremiah A Johnson

Macromolecules 2018 51 (23), 9861-9870

11. Immunomodulation of the NLRP3 inflammasome through structure-based activator design and functional regulation via lysosomal rupture

Mark E Johnson, Judy Shon, Brian M Guan, Joseph P Patterson, Nathan J Oldenhuis, Alexander C Eldredge, Nathan C Gianneschi, Zhibin Guan

ACS Central Science 2018 4 (8), 982-995

10. Large continuous mechanical gradient formation via metal–ligand interactions

James A Neal, Nathan J Oldenhuis, Andrea L Novitsky, Emil M Samson, William J Thrift, Regina Ragan, Zhibin Guan

Angewandte Chemie International Edition 2017 56 (49), 15575-15579

9. Potent Antifungal Synergy of Phthalazinone and Isoquinolones with Azoles Against Candida albicans

Aaron D Mood, Ilandari Dewage Udara Anulal Premachandra, Stanley Hiew, Fuqiang Wang, Kevin A Scott, Nathan J Oldenhuis, Haoping Liu, David L Van Vranken

ACS Medicinal Chemistry Letters 2017 8 (2), 168-173

8. Focused library approach to discover discrete dipeptide bolaamphiphiles for siRNA delivery

Mark E Johnson, Judy Shon, Brian M Guan, Joseph P Patterson, Nathan J Oldenhuis, Alexander C Eldredge, Nathan C Gianneschi, Zhibin Guan

Bioconjugate Chemistry 2016 27 (8), 1784-1788

7. Biodegradable dendronized polymers for efficient mRNA delivery

Nathan J Oldenhuis, Alexander C Eldredge, Alan O Burts, Keun Ah Ryu, Jae Chung, Mark E Johnson, Zhibin Guan

ChemistrySelect 2016 1 (15), 4413-4417

6. Fluorocarbon modified low-molecular-weight polyethylenimine for siRNA delivery

Mark E Johnson, Judy Shon, Brian M Guan, Joseph P Patterson, Nathan J Oldenhuis, Alexander C Eldredge, Nathan C Gianneschi, Zhibin Guan

Bioconjugate Chemistry 2016 27 (8), 1784-1788

5. Structure-based design of dendritic peptide bolaamphiphiles for siRNA delivery

Hanxiang Zeng, Mark E Johnson, Nathan J Oldenhuis, Timothy N Tiambeng, Zhibin Guan

ACS Central Science 2015 1 (6), 303-312

4. From racemic alcohols to enantiopure amines: Ru-catalyzed diastereoselective amination

Nathan J Oldenhuis, Vy M Dong, Zhibin Guan

Journal of the American Chemical Society 2014 136 (36), 12548-12551

3. Catalytic acceptorless dehydrogenations: Ru-Macho catalyzed construction of amides and imines

Nathan J Oldenhuis, Vy M Dong, Zhibin Guan

Tetrahedron 2014 70 (27-28), 4213-4218

2. Mild and General Conditions for Negishi Cross‐Coupling Enabled by the Use of Palladacycle Precatalysts

Yang Yang, Nathan J Oldenhuis, Stephen L Buchwald

Angewandte Chemie International Edition 2013 52 (2), 615-619

1. Synthesis of unsymmetrical diarylureas via Pd-catalyzed C–N cross-coupling reactions

Simon Breitler, Nathan J Oldenhuis, Brett P Fors, Stephen L Buchwald

Organic letters 2011 13 (12), 3262-3265

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