publications | natolab

natolab publications

For a full current list of publications check out Nate's google scholar page

7. Strain-Accelerated β-Thiolactone Native Chemical Ligation with Kinetic Control Enables Rapid and Selective Hydrogelation for Biofabrication

Matthew E. Currier, Tran M. Truong, Dylan M. Sager, Kaelin E. Marshall, Linqing Li, Nathan J. Oldenhuis

Journal of the American Chemical society 2026 Accepted

ChemArxiv Link

6. Designing Thermally Stable DNA Hydrogels via Entropically‐Driven Acridine Intercalation

Shaina M. Hughes, Amy M. DiVito, Pearson J.J. Franz, Mathew E. Currier, Nathan J. Oldenhuis

Macromolecular Rapid Communication 2026 Accepted

5. Solvent-Directed Phase Control in Disulfide-Linked Metal-Organic Frameworks Revealed by Microcrystal Electron Diffraction

Patrick F. Strobel, Lucas Laventure, Priyanshu Chandra, Mark Del Campo, Pierre Le Magueres, Luaren Aheran, Jing Jin, Nathan J. Oldenhuis, David Punihaole, Aylin Aykanat

Precision Chemistry 2026 Accepted

4. Transforming bio-derived DNA into biotechnology

Wynter A. Paiva, Matthew E. Currier, Samuel E. Ashooh, Noelle M. Honan, Nathan J. Oldenhuis

Trends in Chemistry 2025, 12, 884[PDF]

3. Generation of topologically defined linear and cyclic DNA bottle brush polymers via a graft-to approach

Nicholas G Pierini,* Wynter A Paiva,* Owen C Durant, Aubrianna M Dobbins, Ben B Wheeler, Matthew E Currier, James Vesenka, Nathan J Oldenhuis

*Denotes Equal Contribution

Polymer Chemistry 2025, 16, 2646 [PDF]

2. DNA-Intercalating Supramolecular Hydrogels for Tunable Thermal and Viscoelastic Properties

Shaina M. Hughes,* Aylin Aykanat,* Nicholas G. Pierini, Wynter A. Paiva, April A. Weeks, Austin S. Edwards, Owen C. Durant, Nathan John Oldenhuis

*Denotes Equal Contribution

Angewandte Chemie International Edition 2024 63, e202411115 [PDF]

1. From Bioreactor to Bulk Rheology: Achieving Scalable Production of Highly Concentrated Circular DNA

Wynter A Paiva, Somkene D Alakwe, Juexin Marfai, Madigan Jennison‐Henderson, Rachel A Achong, Tinotenda Duche, April Weeks, Rae M Robertson‐Anderson, Nathan J Oldenhuis

Advanced Materials, 2024 2405490 [PDF]

Previous Publications

From undergraduate, graduate, and postdoctoral studies

18. Nested non-covalent interactions expand the functions of supramolecular polymer networks

David J Lundberg, Christopher M Brown, Eduard O Bobylev, Nathan J Oldenhuis, Yasmeen S Alfaraj, Julia Zhao, Ilia Kevlishvili, Heather J Kulik, Jeremiah A Johnson

Nature Communications 2024 15 (1), 3951

17. Photoswitchable Sol–Gel Transitions and Catalysis Mediated by Polymer Networks with Coumarin‐Decorated Cu24L24 Metal–Organic Cages as Junctions

Nathan J Oldenhuis, K Peter Qin, Shu Wang, Hong‐Zhou Ye, Eric A Alt, Adam P Willard, Troy Van Voorhis, Stephen L Craig, Jeremiah A Johnson

Angewandte Chemie International Edition 2022 59 (7), 2784-2792

16. Polymer Networks with Cubic, Mixed Pd(II) and Pt(II) M6L12 Metal–Organic Cage Junctions: Synthesis and Stress Relaxation Behavior

Julia Zhao, Eduard O Bobylev, David J Lundberg, Nathan J Oldenhuis, Heng Wang, Ilia Kevlishvili, Stephen L Craig, Heather J Kulik, Xiaopeng Li, Jeremiah A Johnson

Journal of the American Chemical Society 2023 145 (40), 21879-21885

15. Endohedrally functionalized metal–organic cage-cross-linked polymer gels as modular heterogeneous catalysts

Christopher M Brown, David J Lundberg, Jessica R Lamb, Ilia Kevlishvili, Denise Kleinschmidt, Yasmeen S Alfaraj, Heather J Kulik, Maria Francesca Ottaviani, Nathan J Oldenhuis, Jeremiah A Johnson

Journal of the American Chemical Society 2022 144 (29), 13276-13284

14. Greener methods for amide bond synthesis

Nathan J Oldenhuis, Aaron M Whittaker, Vy M Dong

Green Chemistry in Drug Discovery: From Academia to Industry, 2022 35-96

13. Photoswitchable Sol–Gel Transitions and Catalysis Mediated by Polymer Networks with Coumarin‐Decorated Cu24L24 Metal–Organic Cages as Junctions

Nathan J Oldenhuis, K Peter Qin, Shu Wang, Hong‐Zhou Ye, Eric A Alt, Adam P Willard, Troy Van Voorhis, Stephen L Craig, Jeremiah A Johnson

Angewandte Chemie International Edition 2020 59 (7), 2784-2792

12. Brush-first and ROMP-out with functional (macro) monomers: method development, structural investigations, and applications of an expanded brush-arm star polymer platform

Matthew R Golder, Hung V-T Nguyen, Nathan J Oldenhuis, Julian Grundler, Ellane J Park, Jeremiah A Johnson

Macromolecules 2018 51 (23), 9861-9870

11. Immunomodulation of the NLRP3 inflammasome through structure-based activator design and functional regulation via lysosomal rupture

Mark E Johnson, Judy Shon, Brian M Guan, Joseph P Patterson, Nathan J Oldenhuis, Alexander C Eldredge, Nathan C Gianneschi, Zhibin Guan

ACS Central Science 2018 4 (8), 982-995

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natolab publications

7. Strain-Accelerated β-Thiolactone Native Chemical Ligation with Kinetic Control Enables Rapid and Selective Hydrogelation for Biofabrication

6. Designing Thermally Stable DNA Hydrogels via Entropically‐Driven Acridine Intercalation

5. Solvent-Directed Phase Control in Disulfide-Linked Metal-Organic Frameworks Revealed by Microcrystal Electron Diffraction

4. Transforming bio-derived DNA into biotechnology

3. Generation of topologically defined linear and cyclic DNA bottle brush polymers via a graft-to approach

2. DNA-Intercalating Supramolecular Hydrogels for Tunable Thermal and Viscoelastic Properties

1. From Bioreactor to Bulk Rheology: Achieving Scalable Production of Highly Concentrated Circular DNA

Previous Publications

18. Nested non-covalent interactions expand the functions of supramolecular polymer networks

17. Photoswitchable Sol–Gel Transitions and Catalysis Mediated by Polymer Networks with Coumarin‐Decorated Cu24L24 Metal–Organic Cages as Junctions

16. Polymer Networks with Cubic, Mixed Pd(II) and Pt(II) M6L12 Metal–Organic Cage Junctions: Synthesis and Stress Relaxation Behavior

15. Endohedrally functionalized metal–organic cage-cross-linked polymer gels as modular heterogeneous catalysts

14. Greener methods for amide bond synthesis

13. Photoswitchable Sol–Gel Transitions and Catalysis Mediated by Polymer Networks with Coumarin‐Decorated Cu24L24 Metal–Organic Cages as Junctions

12. Brush-first and ROMP-out with functional (macro) monomers: method development, structural investigations, and applications of an expanded brush-arm star polymer platform

11. Immunomodulation of the NLRP3 inflammasome through structure-based activator design and functional regulation via lysosomal rupture

10. Large continuous mechanical gradient formation via metal–ligand interactions

9. Potent Antifungal Synergy of Phthalazinone and Isoquinolones with Azoles Against Candida albicans

8. Focused library approach to discover discrete dipeptide bolaamphiphiles for siRNA delivery

7. Biodegradable dendronized polymers for efficient mRNA delivery

6. Fluorocarbon modified low-molecular-weight polyethylenimine for siRNA delivery

5. Structure-based design of dendritic peptide bolaamphiphiles for siRNA delivery

4. From racemic alcohols to enantiopure amines: Ru-catalyzed diastereoselective amination

3. Catalytic acceptorless dehydrogenations: Ru-Macho catalyzed construction of amides and imines

2. Mild and General Conditions for Negishi Cross‐Coupling Enabled by the Use of Palladacycle Precatalysts

1. Synthesis of unsymmetrical diarylureas via Pd-catalyzed C–N cross-coupling reactions